Eliminating the most neglected tropical diseases
Nearly one billion people in the world are affected by neglected tropical diseases. These debilitating infectious diseases strike almost exclusively in developing countries (1).
Thanks to this alliance, over 170,000 people with sleeping sickness have received treatment (2). Current treatments are, however, often poorly tolerated and require several intravenous infusions, which further complicates access to care. This is why Sanofi, in partnership with the Drugs for Neglected Diseases initiative (DNDi), is working to develop a promising new oral treatment for sleeping sickness. All these initiatives aim to eliminate the disease by 2020 (3).
Each year, 1.3 million new cases of leishmaniasis and 20,000 to 30,000 deaths due to the disease are reported worldwide. The most common form of this parasitic disease, which is transmitted by the bite of an insect, is the cutaneous form, which causes ulcers and severe disability (4).
The Sanofi plant in Suzano (Brazil) produces a drug used in first-line treatment of leishmaniasis. Sanofi provides the drug at a preferential price in all developing countries. Today it is administered by injection only, but our research teams are also working to develop a treatment for ulcers that could be applied to the skin.
Lymphatic filariasis (or elephantiasis) is a threat to more than 1.4 billion people in 73 countries. Among them, over 120 million are currently infected, with about 40 million people disfigured and incapacitated by the disease (5).
Together with the Japanese firm Eisai and the Bill & Melinda Gates Foundation, Sanofi is a partner in the WHO’s Global Program to Eliminate Lymphatic Filariasis (elephantiasis) by 2020 (3). We have committed, alongside our partners, to donate 120 million tablets of diethylcarbamazine citrate (DEC) in 2012 and 2013, which will enable the WHO to provide treatment for 30 million people.
Within the framework of our partnership with the WHO, Sanofi also contributes to:
1. WHO, “Working to overcome the global impact of neglected tropical diseases,” First WHO report on neglected tropical diseases, 2011.
March 05, 2014
February 25, 2014